产品货号：
Z30535
中文名称：
ZCCHC11抗体
英文名称：
Anti-ZCCHC11 antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZCCHC11 antibody |
| 指标别名 | Terminal uridylyltransferase 4;TUTase 4;2.7.7.52;Zinc finger CCHC domain-containing protein 11;Zcchc11;Kiaa0191;Tut4 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,ICC/IF,IP,ELISA |
| 基因名称 | ZCCHC11 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Peptide |
| 实际分子量 | 3 |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ZCCHC11,also named as KIAA0191 and TUT4,is an uridylyltransferase that acts as a suppressor of microRNA (miRNA) biogenesis by specifically mediating the terminal uridylation of some miRNAs.ZCCHC11 catalyzes the 3' uridylation of precursor let-7 (pre-let-7),a miRNA precursor.Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation.Degradation of pre-let-7 contributes to the maintenance of embryonic stem (ES) cells and is required for ES cells to maintain pluripotency.ZCCHC11 can't bind RNA by itself,recruited to pre-let-7 miRNAs via its interaction with LIN28 and LIN28B.Also catalyzes the 3' uridylation of miR-26A,a miRNA that represses IL6 transcript,leading to abrogate IL6 transcript repression and promote cytokine expression.ZCCHC11 may also suppress Toll-like receptor-induced NF-kappa-B activity via binding to T2BP.This antibody is specifical to the 185 kd ZCCHCC11 protein. |
| Uniprot ID | Q5TAX3 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | terminal uridylyl transferase 4 |
| 蛋白名全称 | Terminal uridylyltransferase 4 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Enzyme linked immunosorbent assay (ELISA) 1:100～1000 |
相关搜索：ZCCHC11抗体，ZCCHC11多抗，Anti-ZCCHC11 antibody